書籍詳細

書籍詳細




洋書

遺伝子、環境とアルツハイマー病

Genes, Environment and Alzheimer's Disease

Lazarov, Orly (EDT)   Tesco, Giuseppina (EDT)

Academic Pr 2016/04
448 p. 24 cm   
装丁: Hrd    装丁について
テキストの言語: ENG    出版国: US
ISBN: 9780128028513
KCN: 1023607145
紀伊國屋書店 選定タイトル
標準価格:¥14,732(本体 ¥13,393)   
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納期について
DDC: 573
KDC: G70 神経内科学・神経科学
関連書リスト: SB2812B エルゼビア社 心理学・神経科学 関連書 特集
SB2855A 神経科学 関連書 特集
SB2892C 学術洋書 在庫特価キャンペーン 2017
ND1305
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Annotation

Provides the first volume to link genetic and environmental risk factors for alzheimer's disease and dementia.

Full Description

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer's disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.

Table of Contents

1. What Is Cognition? Molecular Mechanisms of Learning and Memory Daniela Puzzo, Jole Fiorito, Rosita Purgatorio, Walter Gulisano, Agostino Palmeri, Ottavio Arancio and Russell Nicholls 2. When Cognitive Decline Becomes Pathology: From Normal Aging to Alzheimer's Disease Eliezer Masliah and David P. Salmon 3. Adult Neurogenesis and Cognitive Function Keri Martinowich and Robert J. Schloesser SECTION I. Genetic Forms of AD 4. APP and Cognition Robert Marr 5. FAD Signaling, PS and Cognition Li Gan SECTION II. Environmental Factors 6. The effect of APOE genotype on amyloid-independent mechanisms Guojun Bu 7. Lifestyle and AD Orly Lazarov 8. Bace and Cognition Giuseppina Tesco 9. Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury Douglas H. Smith 10. Alzheimer's Disease and the Sleep-Wake Cycle Adam W. Bero and Li-Huei Tsai 11. Stroke, Cognitive Function and Alzheimer's Disease Katherine A. Jackman 12. Cerebral innate immunity: a new conceptual framework for Alzheimer's David Gate and Terrence Town 13. Type 2 Diabetes and AD Marcelo Bonini