書籍詳細

書籍詳細




洋書

免疫の思想史

Immunity : The Evolution of an Idea

Tauber, Alfred I.

Oxford Univ Pr 2017/01
303 p. 25 cm   
装丁: Hrd    装丁について
テキストの言語: ENG    出版国: GB
ISBN: 9780190651244
装丁違いISBN: 019091419X
KCN: 1026071575
紀伊國屋書店 選定タイトル
標準価格:¥13,026(本体 ¥11,842)   
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納期について
DDC: 616.079
KDC: A116 科学史・科学哲学
G05 科学史・科学哲学
M43
書評掲載: Choice Reviews 2017 October
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Annotation

New in paperback. Hardcover was published in 2017.

Full Description

Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception.

Table of Contents

Preface Acknowledgements Introduction Chapter 1: A History of the Immune Self Chapter 2: Whither Immune Identity? Chapter 3: Individuality Revised Chapter 4: Immune Cognition Chapter 5: Eco-immunology Chapter 6: A New Biology? Epilogue Endnotes References