Discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes.
Integrating scientific knowledge with today's most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment. Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment. Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions. Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics. Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders. Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines. Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals. Includes contributions from expert international authors, making this a truly global reference to addiction medicine. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Table of Contents
Part I: History, Perspective, Epidemiology, Dx and Classification 1. Emerging Health Perspectives 2. The Epidemiology of Alcohol and Drug Disorders 3. United States Federal Drug Policy 4. Historical Perspectives of Addiction 5. Diagnosis and Classification of Substance Use Disorders Part II: Behavioral Theories for Substance Use Disorder 6. Drug Reinforcement in Animals 7. Role of the Human Laboratory Studies in the Development of Medications for Alcohol and Substance Abuse Disorders 8. Conditioning of Addiction 9. Overlapping Striatal Circuits and Molecular Mechanisms in Rodent Models of Addiction and Depression 10. The Role of Endocannabinoids in Amphetamine-Driven Actions in Dopamine Neurons: Implications for Understanding and Treating Dysfunction in the Mesolimbic Circuit 11. Pain and Negative Affect 12. Genetic Vulnerability to Substance Use Disorders 13. Assessment and Treatment of Addiction in Best Practices and New Frontiers in a Direct to Consumer Age 14. Metabolomics in Drug Response and Addiction Part III: Visualizations and Workings of the Addicted Brain 15. Visualization and Workings of the Addicted Brain 16. Neurobiological Basis of Drug Reward and Reinforcement 17. Neurobehavioral Toxicology of Substances of Abuse 18. Animal Models of Substance Use Disorders: Motivational Perspective 19. Novel Methodologies: Proteomic Approaches in Substance Abuse Research 20. Neuroinflammatory Processes in Drug Addiction Part IV: Clinical Aspects of Alcohol and Drug Addiction 21. Alcohol: Clinical Aspects 22. Cocaine 23. Nicotine 24. Cannabis: An Overview of the Empirical Literature 25. Opiates and Prescription Drugs 26. Clinical Aspects of Methamphetamine 27. Sedative-Hypnotics and Anxiolytics 28. Clinical Aspects of Inhalant Addiction 29. Anabolic-Androgenic Steroids 30. Caffeine 31. Serotonergic Hallucinogens 32. Ketamine and Phencyclidine Part V: Behavioral Addictions and Treatment 33. The Biology and Treatment of Pathological Gambling 34. Implications of "Food Addiction" for Understanding and Treating Binge Eating Disorder 35. Compulsive Buying 36. Sexual Behavior as an Addictive or Compulsive Phenomenon 37. New Era of Internet Addiction Research in China 38. Hoarding as a Behavioral Addiction Part VI: Treatment and Application: Behavioral Treatments 39. Motivational Interviewing: Emerging Theory, Research, and Practice 40. Cognitive Behavioral Therapy for Addiction 41. Community Reinforcement Approach and Contingency Management Therapies 42. Relapse Prevention and Recycling in Addiction 43. Brief and e-Health Interventions for the Treatment of Alcohol or Other Drug Addiction 44. Self-Help Approaches for Addiction Section VII: Treatment and Application: Group Treatments and Specific Settings 45. Community Clinics 46. Unhealthy Alcohol and Other Drug Use in Primary Care 47. Criminal Justice System and Addiction Treatment 48. Adolescent Neurocognitive Development and School-Based Drug Abuse Prevention and Treatment 49. The Therapeutic Community for Drug-Abuse Treatment: A Journey Yet Unfolding in the Recovery Movement 50. Substance Use-Focused Mutual-Help Groups: Processes and Outcomes Section VIII: Treatment and Application Pharmacotherapy 51. Pharmacotherapy for Alcoholism and Some Related Psychiatric and Addictive Disorders: Scientific Basis and Clinical Findings 52. Alcohol Withdrawal: Treatment and Application 53. Pharmacotherapy of Cocaine Addiction 54. Opioid Overdose 55. Methamphetamine 56. Potential Pharmacotherapies for Cannabis Dependence 57. Hallucinogens Section IX: Molecular Genetics, Alternative Therapies, and Other Topics in the Treatment of Addiction 58. Molecular Genetics and the Treatment of Addiction 59. Physical Considerations for Treatment Complications of Alcohol and Drug Use and Misuse 60. Quadruple Diagnosis: Substance Use Disorder, Comorbid Psychopathology, Human Immunodeficiency Virus Infection, and Hepatitis C Virus Infection 61. Substance Use Stigma as a Barrrier to Treatment and Recovery 62. Religiousness, Spirituality, and Addiction: An Evidence-Based Review Section X: Computer Modeling 63. In Silico Models of Alcohol Kinetics: A Deterministic Approach 64. In Silico Models of Alcohol Dependence Treatment: Stochastic Approach 65. Dynamic and Systems-Based Models for Evaluating Hypotheses Related to Predicting Treatment Response Part XI: Dependence in Specific Populations 66. Enhancing Positive Outcomes for Children of Substance-Abusing Parents 67. Alcohol and Substance Abuse in African Americans 68. Gays, Lesbians, and Bisexuals 69. Substance Use Disorders in Health Care Professionals 70. Identification and Treatment of Alcohol or Drug Dependence in the Elderly 71. Alcohol and Drugs of Abuse in Pregnant Women: Effects on Fetus and Newborn, Mode of Action, and Maternal Treatment Part XII: Legal, Disability and Rehabilitative Issues 72. Forensic Issues 73. Disability and Addiction 74. The Homeless 75. To Open Up New Vistas in Basic and Preclinical Addiction Research