診断病理学：頭頸部（第３版）Diagnostic Pathology: Head and Neck
（Diagnostic Pathology）
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Covering all areas of head and neck pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Head and Neck is a one-stop reference for accurate, complete pathology reports - ideal as a day-to-day reference or as a reliable teaching resource. Prev.ed.: 2016.
Full Description
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of head and neck pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Head and Neck is a one-stop reference for accurate, complete pathology reports-ideal as a day-to-day reference or as a reliable teaching resource.
Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 325 new or evolving entities of the head and neck and endocrine organs
Features updates on recent changes in the field and current information from the AJCC Cancer Staging Manual, 8th Edition, and the World Health Organization Classification of Head and Neck Tumours, 5th Edition
Covers numerous new diagnostic entities, including intraductal carcinoma, sclerosing polycystic adenoma, microsecretory adenocarcinoma, adamantinoma-like Ewing sarcoma, SMARCB1- and SMARCA4-deficient carcinomas, and HPV-related multiphenotypic sinonasal carcinoma
Contains major updates on sinonasal tract, salivary gland, and odontogenic tumors; oropharyngeal squamous cell carcinoma and its correct classification and staging; the recent significant reclassification of neuroendocrine tumors; and changes in terminology and identification for head and neck soft tissue tumors
Suggests supporting studies in a realistic clinical context, with tables and immunohistochemical charts that assist with management decisions and prognostic outcome predictions
Features more than 3,200 images, including full-color drawings of head and neck anatomy, development pathway drawings, staging protocol illustrations, and genetic pathway graphics; radiologic images, clinical photographs, and gross images; and histology, histochemistry, immunohistochemistry, in situ hybridization, and molecular images; as well as more than 2,600 additional online-only images
Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Table of Contents
SECTION 1: NASAL CAVITY ANDPARANASAL SINUSES
4 Nose and Paranasal Sinuses
Lester D. R. Thompson, MD and Jonathan B. McHugh, MD
CONGENITAL/GENETIC/HEREDITARY
6 Nasal Neuroglial Heterotopia
Lester D. R. Thompson, MD
8 Nasal Dermoid Cyst and Sinus
Lester D. R. Thompson, MD
INFECTIOUS
10 Allergic Fungal Sinusitis
Lester D. R. Thompson, MD
14 Invasive Fungal Rhinosinusitis
Lester D. R. Thompson, MD
16 Mycetoma
Lester D. R. Thompson, MD
17 Rhinoscleroma
Lester D. R. Thompson, MD
18 Rhinosporidiosis
Lester D. R. Thompson, MD
20 Mycobacterium lepraeInfection
Lester D. R. Thompson, MD
INFLAMMATORY-IMMUNE DYSFUNCTION
22 Chronic Rhinosinusitis
Brenda L. Nelson, DDS, MS
26 Granulomatosis With Polyangiitis
Susan Müller, DMD, MS
32 Eosinophilic Angiocentric Fibrosis
Lester D. R. Thompson, MD
REACTIVE AND HAMARTOMAS
36 Sinonasal Inflammatory Polyp Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD
40 Antrochoanal Polyp
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
42 Mucocele of Paranasal Sinus
Lester D. R. Thompson, MD
44 Sinonasal Hamartoma
Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD
50 Nasal Chondromesenchymal Hamartoma
Lester D. R. Thompson, MD
52 Extranodal Sinus Histiocytosis With Massive Lymphadenopathy
Susan Müller, DMD, MS
56 Myospherulosis
Lester D. R. Thompson, MD
BENIGN NEOPLASM
58 Sinonasal Papilloma
Lester D. R. Thompson, MD
66 Pleomorphic Adenoma, Sinonasal Tract
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
68 Meningioma, Sinonasal Tract
Lester D. R. Thompson, MD
72 Ameloblastoma, Sinonasal Tract
Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD
74 Ectopic Pituitary Neuroendocrine Tumor
Lester D. R. Thompson, MD
80 Lobular Capillary Hemangioma (Pyogenic Granuloma)
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
84 Sinonasal Tract Angiofibroma
Lester D. R. Thompson, MD
88 Schwannoma/Neurofibroma, Sinonasal Tract
Lester D. R. Thompson, MD
92 Leiomyoma and Smooth Muscle Tumors of Uncertain Malignant Potential
Lester D. R. Thompson, MD
96 Fibromatosis/Desmoid-Type Fibromatosis
Lester D. R. Thompson, MD
98 Solitary Fibrous Tumor, Sinonasal Tract
Lester D. R. Thompson, MD
BORDERLINE NEOPLASM
102 Glomangiopericytoma
Lester D. R. Thompson, MD
MALIGNANT NEOPLASM
106 Squamous Cell Carcinoma, Sinonasal Tract
Lester D. R. Thompson, MD
114 NUT Carcinoma
Lester D. R. Thompson, MD
116 SWI/SNF Complex-Deficient Sinonasal Carcinomas
Lester D. R. Thompson, MD
120 Lymphoepithelial Carcinoma, Sinonasal Tract
Susan Müller, DMD, MS
122 Sinonasal Undifferentiated Carcinoma
Susan Müller, DMD, MS
128 Teratocarcinosarcoma
Lester D. R. Thompson, MD
134 HPV-Related Multiphenotypic Sinonasal Carcinoma
Lester D. R. Thompson, MD
138 Sinonasal Adenocarcinoma, Intestinal Type
Lester D. R. Thompson, MD
144 Sinonasal Nonintestinal-Nonsalivary Adenocarcinoma
Lester D. R. Thompson, MD
152 Sinonasal Renal Cell-Like Adenocarcinoma
Lester D. R. Thompson, MD
154 Olfactory Neuroblastoma
Lester D. R. Thompson, MD
164 Sinonasal Neuroendocrine Carcinoma
Lester D. R. Thompson, MD
170 Mucosal Melanoma, Sinonasal Tract
Lester D. R. Thompson, MD
176 Alveolar Rhabdomyosarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
182 Ewing Sarcoma, Including Sinonasal Adamantinoma-Like
Lester D. R. Thompson, MD
188 Biphenotypic Sinonasal Sarcoma
Lester D. R. Thompson, MD
192 Leiomyosarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
198 Malignant Peripheral Nerve Sheath Tumor, Sinonasal Tract
Lester D. R. Thompson, MD
202 Fibrosarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
206 Angiosarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
210 Mesenchymal Chondrosarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
212 Undifferentiated Pleomorphic Sarcoma, Sinonasal Tract
Lester D. R. Thompson, MD
216 Extranodal NK-/T-Cell Lymphoma, Nasal Type
Aaron Auerbach, MD, MPH
222 Metastatic/Secondary Tumors, Sinonasal Tract
Lester D. R. Thompson, MD
SPECIMEN EXAMINATION, NASAL CAVITY & PARANASAL SINUSES
224 Specimen Examination and Staging Tools, Oropharynx
Lester D. R. Thompson, MD
228 Specimen Examination and Staging Tools, Nasopharynx
Lester D. R. Thompson, MD
SECTION 2: PHARYNX (NASAL, HYPO-)
234 Pharynx
Lester D. R. Thompson, MD and Jonathan B. McHugh, MD
CONGENITAL/GENETIC/HEREDITARY
236 Tornwaldt Cyst
Lester D. R. Thompson, MD
237 Rathke Cleft Cyst
Lester D. R. Thompson, MD
BENIGN NEOPLASM
238 Dermoid
Brenda L. Nelson, DDS, MS
MALIGNANT NEOPLASM
240 Low-Grade Nasopharyngeal Papillary Adenocarcinoma
Lester D. R. Thompson, MD
244 Nasopharyngeal Carcinoma, Nonkeratinizing Types
Susan Müller, DMD, MS and Lester D. R. Thompson, MD
254 Nasopharyngeal Carcinoma, Keratinizing Type
Susan Müller, DMD, MS
256 Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma
Susan Müller, DMD, MS
260 Diffuse Large B-Cell Lymphoma NOS
Aaron Auerbach, MD, MPH
SECTION 3: LARYNX AND TRACHEA
266 Larynx
Lester D. R. Thompson, MD and Jonathan B. McHugh, MD
CONGENITAL/GENETIC/HEREDITARY
268 Laryngocele and Laryngeal Cysts
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
270 Tracheopathia Osteoplastica
Lester D. R. Thompson, MD
INFECTIOUS
272 Laryngitis: Viral, Bacterial, Fungal
Lester D. R. Thompson, MD
REACTIVE
276 Vocal Cord Nodules and Polyps
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
280 Reactive Epithelial Changes
Lester D. R. Thompson, MD
284 Contact Ulcer
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
286 Amyloid (Amyloidoma)
Lester D. R. Thompson, MD
BENIGN NEOPLASM
288 Squamous Papilloma
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
292 Granular Cell Tumor, Larynx
Lester D. R. Thompson, MD
294 Adult Rhabdomyoma
Lester D. R. Thompson, MD
296 Inflammatory Myofibroblastic Tumor
Lester D. R. Thompson, MD
300 Paraganglioma, Larynx
Lester D. R. Thompson, MD
302 Chondroma
Lester D. R. Thompson, MD
BORDERLINE NEOPLASM
304 EBV-Associated Smooth Muscle Tumor
Lester D. R. Thompson, MD
MALIGNANT NEOPLASM
306 Keratinizing Dysplasia and Carcinoma In Situ
Susan Müller, DMD, MS and Lester D. R. Thompson, MD
314 Conventional Squamous Cell Carcinoma
Susan Müller, DMD, MS
322 Verrucous Carcinoma
Susan Müller, DMD, MS
326 Spindle Cell Squamous Cell Carcinoma
Lester D. R. Thompson, MD
332 Papillary Squamous Cell Carcinoma
Lester D. R. Thompson, MD and Susan Müller, DMD, MS
336 Basaloid Squamous Cell Carcinoma
Lester D. R. Thompson, MD
340 Adenosquamous Carcinoma
Lester D. R. Thompson, MD and Susan Müller, DMD, MS
344 Neuroendocrine Neoplasms, Larynx
Lester D. R. Thompson, MD
354 Chondrosarcoma
Lester D. R. Thompson, MD
358 Metastatic/Secondary Tumors, Larynx and Trachea
Lester D. R. Thompson, MD
SPECIMEN EXAMINATION, LARYNX
360 Specimen Examination and Staging Tools, Larynx and Trachea
Lester D. R. Thompson, MD
SECTION 4: ORAL CAVITY
364 Tongue
Lester D. R. Thompson, MD and Jonathan B. McHugh, MD
366 Oral Mucosae
Brenda L. Nelson, DDS, MS
CONGENITAL/GENETIC/HEREDITARY
368 Ectopic (Lingual) Thyroid
Susan Müller, DMD, MS
370 White Sponge Nevus
Susan Müller, DMD, MS
INFECTIOUS
372 Multifocal Epithelial Hyperplasia (Heck Disease)
Susan Müller, DMD, MS
374 Oral Hairy Leukoplakia
Susan Müller, DMD, MS
376 Oral Infections
Susan Müller, DMD, MS
380 Oral Syphilis
Brenda L. Nelson, DDS, MS
INFLAMMATORY-IMMUNE DYSFUNCTION
384 Aphthous Stomatitis
Susan Müller, DMD, MS
390 Pemphigus Vulgaris
Susan Müller, DMD, MS
392 Mucous Membrane Pemphigoid
Susan Müller, DMD, MS
394 Oral Lichen Planus
Susan Müller, DMD, MS
398 Erythema Multiforme
Susan Müller, DMD, MS
400 Lupus Erythematosus
Susan Müller, DMD, MS
REACTIVE
404 Frictional Hyperkeratosis
Susan Müller, DMD, MS
405 Pseudoepitheliomatous Hyperplasia
Susan Müller, DMD, MS
406 Necrotizing Sialometaplasia
Susan Müller, DMD, MS
408 Traumatic Ulcerative Granuloma With Stromal Eosinophilia
Susan Müller, DMD, MS
410 Giant Cell Fibroma
Brenda L. Nelson, DDS, MS
411 Amalgam Tattoo
Susan Müller, DMD, MS
412 Tobacco Changes
Brenda L. Nelson, DDS, MS
414 Parulis
Brenda L. Nelson, DDS, MS
NONNEOPLASTIC LESIONS
415 Fordyce Granules
Susan Müller, DMD, MS
416 Mucocele and Ranula
Susan Müller, DMD, MS
418 Verruciform Xanthoma
Susan Müller, DMD, MS
419 Hairy Tongue
Brenda L. Nelson, DDS, MS
420 Geographic Tongue
Brenda L. Nelson, DDS, MS
422 Juxtaoral Organ of Chievitz
Susan Müller, DMD, MS
423 Heterotopic Salivary Glands
Brenda L. Nelson, DDS, MS
BENIGN NEOPLASM
424 Squamous Papilloma (Including Verruca and Condyloma)
Susan Müller, DMD, MS
428 Fibroma, Oral Cavity
Brenda L. Nelson, DDS, MS
430 Pyogenic Granuloma
Susan Müller, DMD, MS
432 Peripheral Giant Cell Granuloma
Brenda L. Nelson, DDS, MS
434 Peripheral Ossifying Fibroma
Brenda L. Nelson, DDS, MS
436 Mucosal Neuroma
Brenda L. Nelson, DDS, MS
438 Solitary Circumscribed Neuroma
Brenda L. Nelson, DDS, MS
440 Acquired Melanocytic Nevus
Susan Müller, DMD, MS
444 Melanoacanthoma
Susan Müller, DMD, MS
445 Oral Lymphangioma
Susan Müller, DMD, MS
446 Teratoma, Oral Cavity
Brenda L. Nelson, DDS, MS
BORDERLINE NEOPLASM
448 Congenital Granular Cell Epulis
Susan Müller, DMD, MS
450 Granular Cell Tumor, Oral Cavity
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS
454 Melanotic Neuroectodermal Tumor of Infancy
Lester D. R. Thompson, MD
456 Ectomesenchymal Chondromyxoid Tumor
Brenda L. Nelson, DDS, MS
460 GLI1-Altered Soft Tissue Tumor
Lester D. R. Thompson, MD
MALIGNANT NEOPLASM
462 Dyspla