電子書籍詳細

電子書籍詳細


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分子診断学の原理と応用

Principles and Applications of Molecular Diagnostics

Rifai, Nader (EDT)   Horvath, A. Rita (EDT)   Wittwer, Carl T. (EDT)

Elsevier 2018/06
422p.
出版国: US
ISBN: 9780128160619
eISBN: 9780128160626
KNPID: EY00245273
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Full Description

Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments.

  • Explains the principles and tools of molecular biology
  • Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results
  • Provides a detailed description of current molecular applications used to solve diagnostics tasks

Table of Contents

1. Principles of molecular biology 2. Genomes and variants 3. Nucleic acid isolation 4. Nucleic acid techniques 5. Molecular microbiology 6. Genetics 7. Solid tumor genomics 8. Genetic aspects of hematopoietic malignancies 9. Circulating tumor cells 10. Circulating nucleic acids for prenatal diagnostics 11. Pharmacogenetics 12. Identity testing